After a lot of thought I think that it's not anxiolytic in the usual manner; more I felt slightly "distanced" from the world. I haven’t posted in a long time but, if you don’t mind, I’d like to offer my experience with memantine and amphetamine poop-out. This affect was not alarming like a hallucination, but seemed to indicate some kind of minor "glitch" in my brain's visual processing under certain circumstances. “This is the big one, and the one I have the least direct experience with, but it’s been an open secret for some time. Learn … Then do the same in reverse if you decide to stop taking it. From Reddit Collection. Press question mark to learn the rest of the keyboard shortcuts. She began to experience side effects and her doctor determined that we should take her back off. As soon as I got it, I stupidly took a recreational dose of 50mg when the original reason I purchased it was to help with my gabapentin and eventually ativan taper. –Reddit user review I honestly could not tell that it had made any difference whatsoever, but it might have been too short of a period to tell. I was not worried as this is normal at first; Memantine is potently anticholinergic (very specific though, a sub-unit of the nicotinic acetylcholine receptors) and so often has a negative effect on memory that rapidly balances out as the affected receptor upregulates. So far this is working. Donate $500 or more and get a beautiful Huichol yarn painting, hand made by Huichol artists in Mexico. Did you try combining it with a stimulant at any point? An Experience with Memantine. However, the drug does not cure Alzheimer’s. Erowid Relies on Donations From Visitors Like You. The memory issues returned, but to a lesser degree and went away quickly. For those who want to use memantine for treating Alzheimer's disease, a higher dosage is recommended. what have your experiences been with memantine? It is prescribed for people with moderate or severe Alzheimer's disease, who for some reason cannot take the other medicines more usually prescribed for Alzheimer's disease. I’m sorry to read about your mum’s decline, I know how horrible it is when that happens. Buy Memantine From These Trusted Sources. Then after a week it started to settle down until I upped the dosage which left me with brain fog to the point of being scared to drive. User Reviews for Memantine. Memantine is a prescription drug used to treat moderate to severe confusion related to Alzheimer's disease.It does not cure Alzheimer's disease, but it may improve memory, awareness, and the ability to perform daily functions.This medication works by blocking the action of a certain natural substance in the brain that is believed to be linked to symptoms of Alzheimer's disease. Memantine, or 3,5-dimethyladamantan-1-amine, is a man-made molecule classified as a substituted adamantane derivative. mean? My mom was on memantine for a short period of time. Now however, I'm on 10mg B.I.D. Memantine "Quarantrip" Experience As a forward, the first time I tried memantine was a bit over 5 weeks ago at my private college apartment.The dosage was 73mg and the experience was enjoyable and unique. Memantine Dosage. 'Useful But Not Recreational' by rararagi. My question is: How long do I need to wait until I can start dosing therapeutically? The only noticeable side-effect I experienced was a minor, though odd visual abberation; I noticed that moving patterns very noticeably flickered as if under a strobe light. Memantine is substituted with a methyl carbon at both R3 and R5; it contains an amine substitution at R1. If you have ADHD, you need to try this…I’ve been on Memantine at 10mg/day for over a month now. One interesting memantine side effect includes higher libido. More specifically, I felt like my mind was a bit less "pressured", as if I could slow down slightly instead of always being in a "frantic mode" while thinking on the fly (such as in social situations). I don't feel that the effect of coffee has been heightened at all, I just feel a more steady stream of energy throughout the day regardless of what I take for stimulation. Its core structure is adamantane, a diamondoid of four interlocked cyclohexane rings in a stable 3-dimensional lattice conformation. I suggest starting with 2.5mg and not going past that for at least a week. Anyone who has had a relative with Alzheimer’s or dementia can tell you, there are good days and bad days. On the good days, when Joe is at his most lucid, his campaign manager Jen will send him out for photo ops or TV interviews… make hay while the sun is shining, … Also known as: Namenda, Namenda XR Memantine has an average rating of 5.3 out of 10 from a total of 55 ratings on Drugs.com. Useful But Not Recreational. So I have some liquid memantine. The anxiolytic effects remained. It gave me the ability to visualize complex holograms above myself and make edits to them. I actually think it's helped me turn a corner on my anxiety, which has been pretty bad the last couple of years and has ramped up the last few months. I just wanted to take this opportunity to share my memantine experience and hopefully provide some useful information for anyone considering purchasing/using this as an AD. I just wanted to take this opportunity to share my memantine experience and hopefully provide some useful information for anyone considering purchasing/using this as an AD. Hey GetHyyer! (its still going) I'm not even sure where to begin, but note that I am still currently under the effects of the Memantine, so parts of this may not make sense until I edit them in days to come. An Experience with Memantine. I don't know that this is that I'm actually less tired or just that I'm less sensitive to the feeling of being tired. They all seem to be really emotionally charged memories hence why I used the word repressed, but nothing particularly traumatic. Consider a 2020 contribution! Pharms - Memantine Reports (also Namenda) (27 Total) General: First Times: Combinations: Retrospective / Summary: Difficult Experiences: Health Problems : Train Wrecks & Trip Disasters: Glowing Experiences: Mystical Experiences: Medical Use : General » » » more » » »  Wintry Void: nervewing: Memantine & … I haven't got any personal experience with this combination, but I do know that memantine has been implicated in reducing tolerance to GABA agonists (most commonly benzodiazepenes), and so theoretically it should reduce tolerance to phenibut and lead to more pronounced effects. I've developed a strange tenacity even when I am tired. I light up a cigarette, like after most meals, and notice the slow whisps of smoke dancing around my hand, this is when I remembered about the Memantine, about 2 hours after taking the dose. Right out of the gate I'll say that my experience has been overwhelmingly positive. Memantine has de-emphasized the NMDA/nACh and allowed my to use NSI-189 without the accompanying anxiety that it's caused me before. Consequently, there is a large pool of high-quality evidence that supports memantine’s use in moderate-to-severe cases of Alzheimer’s disease (AD). Has anyone else had this experience? Anyways, the pronounced memory impairment went away as expected. It is ... A study examining self-reported misuse of memantine on the social network reddit shown that the drug was used as a recreational drug and as a nootropic, but also that it was misused in various illnesses as self-medication without strong scientific basis. Did you combined campral with memantine? it seemed so futuristic. Overall I would say I like it but stay closer to approved dosages probably. I've since quit taking it simply cause I'm trying to not use any substances at all for a while but I definitely don't notice any long term effects. i've only heard of people using much smaller doses. Like a very strong dissociative, but it is not pleasurable at all. So, I think if you are very careful, 2.5mg every 2 days until you really get a feel for it, you will be fine. Good to know that you did well with Memantine at reasonable dosage, i will get the campral soon and will tell you how it works for me. Then after a week it started to settle down until I upped the dosage which left me with brain fog to the point of being scared to drive. I also did not experience any major benefits; my feelings were mixed about the anxiolytic effects. I saw my ex-girlfriend in a wedding dress. I tend to run 10mg every 80 hours, depending on how I feel. Stunning Huichol Yarn Art . I keep reading about it and am excited by it, but I fear being dysfunctional and/or having bad DP/DR and losing my shit. I want to experience: Lsd + Memantine DOB + memantine Apollo Neuro Wearable. I like using ashwagandha and Memantine together. It was first developed in the 1960s for the treatment of diabetes. Soon after I started to feel more connected; to myself and others. Its name is derived from its structure; 3,5-dimethyladamantan-1-amine. Toute reproduction ou représentation totale ou partielle de ce site par quelque procédé que ce … We're an educational non-profit working to provide a balanced, honest look at psychoactive drugs and drug use--to reduce harms, improve benefits, and support policy reform. What does B.I.D. A categorized index of first-person experiences with Pharms - Memantine. I'm simply saying the initial acute effects of brain-fog weren't a horrible experience as I started from a very low dose and kept it low until the effect dissipated (I hope that makes sense). Memantine is a medication used to treat moderate-to-severe Alzheimer's disease. Although there is moderate-certainty evidence that fewer people taking memantine experience agitation as an adverse event: RR 0.81 (95% CI 0.66 to 0.99) (25 fewer people per 1000, 95% CI 1 to 44 fewer), there is also moderate-certainty evidence, from three additional studies, suggesting that memantine is not beneficial as a treatment for agitation (e.g. Being Disconnected From Reality. Anxiety, restlessness, brain fog. I started with 5mg and didn't feel much the first day and took more the second and then it all kicked in and I felt like what you would feel like if you took 200mg of benadryl. That being said, does anyone care to shed some light on long term use of memantine? Both the research  and anecdotal reports  recount as much. However, I also noticed that I felt a bit slow, and my memory was definitely fuzzy for the first week (I'd abruptly lose track of a conversation or even my train of thought while speaking). I'm on day seven and I've noticed that I keep recalling what seem to be repressed or mostly forgotten memories. I have ADD and severe OCD and am about to embark on a Memantine trial; people with ADD plus dysthymic type depression have reported that the combination (Memantine plus stimulant) is very effective, since Memantine helps prevent tolerance to the more upbeat, life-affirming qualities of stims..whereas Memantine on its own can have a slight flattening effect. Additionally I should note that I tend to feel less tired throughout the day. Memantine oral tablet is a prescription medication used to treat moderate to severe dementia caused by Alzheimer’s disease. My understanding is it usually takes 2 days to 2 weeks at most for this affect to resolve itself. Search for: Recommended Biohacks. I was on it for another 4 weeks without dosing changes. Most studies support 20mg a day (or 10mg twice daily) to be the most … oddly as I got more sober they became more tangible. TL;DR All in all I did not notice any large benefits. My experience with Memantine has been quite the journey. Be very careful with dosing it. Ok, as someone who just went through a painful experience I will tell you this. I'm also taking and 9 methyl beta carboline for DA effects. Lying in bed that night I had a psychadelic self healing experience where all the lessons I have been learning, all the new friends I have made, started coming back to me, and resonating on a deep level. MEMANTINE HYDROCHLORIDE NICHE 20MG FILM-COATED TABLETS (Leaflet) MEMANTINE HYDROCHLORIDE TEVA 10MG/ML ORAL SOLUTION (Leaflet) MEMANTINE HYDROCHLORIDE TORRENT 10 MG/ML ORAL SOLUTION (Leaflet) Ingredient matches for Memantine Hydrochloride Memantine. while it was going on I was convinced that brain scanners could be hooked up to me so that other people could see what was going on. Looks like you're using new Reddit on an old browser. It also keeps my kratom tolerance at bay. For a fuller discussion surrounding nootropics and holistic brain hacking, join our growing community on Facebook!! I did not notice any other side-effects, nor did I experience withdrawal or rebound issues while quitting. it seemed I could control it with my imagination. Memantine is a prescription drug that is also known by the brand name Namenda. I can focus better, it’s easier to motivate myself to get things done, and I’m procrastinating much less than I used to. All the best, I've taken up to 60-70 mg a day after titration to no real I'll effect. At first the sides were terrible. After I've eaten and sat down to begun browsing reddit, the fact I've taken the Memantine has almost completely been forgotten by me, I begin to feel a bit spacey and calm. When the kratom wore off I got anxiety again and was stressed out by every little thing , so I took another 10mg of memantine which is kinda helping a bit. This experience may be in line with what others are reporting in terms of increased sensitivity to coffee/stims etc. It helps reduce dementia symptoms, but it … It was slightly calming, and perhaps this effect could be more pronounced/useful for someone with more severe anxiety issues. Metabolism Tracker. Memantine will be prescribed by a specialist doctor. Brand names. 43% of those users who reviewed Memantine reported a positive effect, while 41% reported a negative effect. I would become very small and see what appeared to be bacteria and cells interacting. Memantine. I glimpsed into this place that looked like interlocking chains, a pit going down endlessly. laid in bed for a couple of days. Pharms - Memantine (309), Sleep Deprivation (140) : General (1), First Times (2), Hangover / Days After (46), Multi-Day Experience (13), Various (28) COPYRIGHTS: All reports are copyright Erowid and you agree not to download or analyze the report data without … Memantine Hydrochloride (BANM, JAN, USAN) is known as Memantine in the US. I seem to remember one member here whose PWD got very good results with memantine, temporarily, but I have no personal experience … I traveled through futuristic city scenes. Lumen. Explore other smart treatment options, see research evidence, and find out about people's experiences with many popular treatments, including feedback from patients and professionals. Not in the potentially worrisome derealization kind of way, but more just sort of "flat" in terms of my feelings. After 2 weeks, I upped the dosing frequency to twice daily as planned. I started taking Memantine this past week. Please share your thoughts in the comments below. by rararagi. I still experienced a normal range of emotions (I still experienced pleasure, still felt sad when expected, still enjoyed humor, etc), but they felt slightly dampened. Discussion of nootropics and cognitive enhancers. Did you had any interactions? Oct 29, 2020 #2 Hi @sammyseal. At first the sides were terrible. Now however, I'm on 10mg B.I.D. took 300 or 400 mg. yeah, I know. grids of squares and circles. I have never demonstrated any warning signs of mental illness myself (and I've been put under long periods of severe stress on multiple occasions, with no sign of any symptoms emerging), nor has my brother. Thanks in advance for your advice and experience - I'm completely lost... Bunpoots Volunteer Host. Right out of the gate I'll say that my experience has been overwhelmingly positive. Pharms - Memantine (309) : Small Group (2-9) (17), Multi-Day Experience (13), Retrospective / Summary (11) COPYRIGHTS: All reports are copyright Erowid and you agree not to download or analyze the report data without contacting Erowid Center and receiving permission first. prior to that I would enter these animated scene and travel through them for 5 minutes until they decayed and dissolved for no reason. I have a post "most beautiful day of my life" regarding my combination of aniracetam with Memantine. The FDA has officially approved memantine for the treatment of certain cases of Alzheimer’s disease, and this is the most typical medical use of memantine. Apr 1, 2016 5,017 0 Nottinghamshire. I did not notice any significant benefit to my cognition or memory. Just a brief intro: I am a guy in my twenties, I have ADD (diagnosed and medicated, though at the time I had not been taking methylphenidate or anything else for a while), mild social anxiety (does not severely affect me, but requires me to make an effort to socialize). Those are my experiences with the above substances, I'd like to research more combinations though and would like input. did you know a dose of that size would give you such an experience? New comments cannot be posted and votes cannot be cast. 12-14 hours of increasingly profound visual hallucination. Anyway, I know this isn't the stackadvice forum but I think my post is mostly pertaining to my experience with memantine (rather than asking for any advice). The most noticeable effect from memantine is that I don't feel anywhere near as burnt-out or deflated on a day to day basis. I will be mindful about the long half life and taper down possibly to 5 mg. My experience is ordering it from Ceretropic and being too scared to try it. Memantine. I ended up cutting the dose back to 5 mg as I approached the end of my supply, and then stopped taking it. Ce document intitulé « MEMANTINE - Indications, posologie et effets secondaires » issu de Journal des Femmes (sante-medecine.journaldesfemmes.fr) est soumis au droit d'auteur. jelly fish made of blue and green light. I've come to the realization that I"m sensitive to choline sources, such that racetams and supplemental choline have really increased the level of anxiety. I took pharmaceutical grade Memantine (the pharmacy dispensed tablet packets), at 5 mg once daily, titrated up to twice daily (so from 5 mg daily to 10 mg daily total, one in the morning and one in the afternoon) after 2 weeks as per the general prescription rules. That being established, I did experience some acute brain-fog as was expected. I experienced no noticeable issues during this time. For a little while it certainly had some dissociative effects but then after that I just felt more detached and could focus on work and things easier. Find more subreddits like r/MemantineHCl -- A sub for discussing all uses of Memantine, from therapeutic to recreational. I would love to reset tolerance to prescribed pain medication but I'm just spooked by the bad reports I have come across - mostly because of the long half-life. They make fabulous gifts! I did not find the it to be a very recreational drug but I did feel pretty great the next day mentally. My experience with Memantine has been quite the journey. This was beneficial in that it seemed to help me feel a little more calm, but it didn't help enough to really warrant the effort it took to obtain reliable quality Memantine (at least at the time; there were no bulk sources available). and have complete control over my ocd, intrusive thoughts, adhd, and anxiety. The site may not work properly if you don't, If you do not update your browser, we suggest you visit, Press J to jump to the feed. “Memantine is the best treatment I have ever tried for ADHD. It's not like that of a stimulant -- I still feel tired -- I just don't have an immediate stressed out/defeated anxious accompaniment when I begin to feel fatigued at the end of the day. Anxiety, restlessness, brain fog. Understand Memantine, usages in various health conditions, and side effects and warnings. Instant Zen . honestly, in the future I think that this is possible. That being established, I did experience some acute brain-fog as was expected. I’ve been taking memantine for about 2 years with adderall. I do emphasize the importance of titrating doses up and down as best possible though; I would not start at 10 mg and I would not abruptly quit from 10 mg. Start at the lowest possible dose, give it 2 weeks, and then double it. It will only be started for people who have a caregiver able to supervise the treatment. (12 & 24 inch pieces available.) hell, im not even certain that if someone else was in the room they could not have seen these holograms; they seemed that real. In 2003, the FDA approved Memantine for the treatment of both severe and moderate Alzheimer’s disease. This thread has me a little worried, especially when I read the word "irreversible." The same thing happened while walking along a brick wall while watching it as I walked. The 20 mg/day memantine dose was associated with a higher rate of completion and larger mean improvement on the ADHD-IV and CGI-S than 10 mg/day memantine. But I titrated up as recommended and I've since settled into a nice "pocket" with dosing. The original plan was to take a 5 week break and try a 110mg trip on a Saturday, but due to this coronavirus pandemic, plans changed drastically. by itstingsandithurts. It's difficult to describe as the effect was very subtle. I was not high all day or anything at the time though, I'd usually only smoke before bed, and skipped days regularly. At first, I found it provided a moderate reduction in anxiety. I've been taking it for more than a week.....10 mg dropper...no titration aside from the first day...just dove right in. and have complete control over my ocd, intrusive thoughts, adhd, and anxiety. Learn More. I have a family history of mental illness; my father has severe bipolar disorder that he has had under control with a mood stabilizer for the last couple of decades. Memantine experience. At the time I smoked weed fairly frequently (multiple times a week), though I quit fairly recently. It was not however as devastating as I was prepared for, and I was still very functional. I didn't notice a huge pronouncement of effects, but they seemed to last more consistently. I did smoke cannabis on and off while using it, without experiencing any negative interaction (it did make me more tired when smoking, but not in an alarming way). Do you have experience supplementing with Memantine? An example of these "patterns" would be if I was walking on a boardwalk, if I looked at the planks while walking, the dark spaces between the slats would produce a very noticeable strobing effect that was clearly not normal. people I used to know. -- although I wouldn't personally describe it that way. Most AEs were mild and occurred during the first week of treatment. It has an 80 hour half life. Memantine - my experience with recreational doses. When I got home I decided to take a large dose of Memantine; about 70mg. The memantine dosage will differ based on the use case. Rather positive or rather negative? Edit: for clarity, I'm not saying that my increasing of the dosing is what is responsible for the brain-fog dissipating. Pharmacokinetic analyses suggest response to memantine may be dose-dependent beyond an initial threshold concentration. 'Being Disconnected From Reality' by itstingsandithurts. … I have experimented with a lot of nootropics and have long gotten over getting hyped up about things (I've tried pretty much all of them, and found most don't do very much for me). Thanks for the review! these holograms would appear in my room and float toward me. Adderall alone will lose its effectiveness with me in a few days if I don’t take it with a drug like memantine. I've shifted my thinking forward to making another purchase from Ceretropic.